FloodLAMP Integrated Clinical Study Design - Digestion Digestion of FloodLAMP's integrated clinical study design (~May-August 2022) that merged an active school-based surveillance program with a clinical trial for generating EUA submission data. Covers the enrichment strategy using school exposures and surveillance-detected positives, a cascading cohort structure for maximizing positive specimen yield, comparator testing efficiency, multi-assay validation design, and RNAseP cross-validation, with both internal and external-facing analyses. ai file regulatory irb _AI_digestion_irb_new-clinical-study-design.md regulatory/irb/_AI_digestion_irb_new-clinical-study-design.md 2026_02_28 Created by Claude Opus 4.6 Max during archive preparation. **NOT HUMAN VERIFIED - MAY CONTAIN ERRORS** Digestion and analysis of FloodLAMP's integrated clinical study design (~May-August 2022), synthesized from planning notes with whiteboard diagram, associated slide deck/GDoc content, and the original IRB protocol (Protocol 20210401). clinical-study, enrichment, surveillance, EUA, study-design, cascading-cohort md CC BY 4.0 - https://creativecommons.org/licenses/by/4.0/ 4378 6018 gfile-url xfile-github-download-url pdf-gdrive-url pdf-github-url github-markdown-url github-markdown-download-url web-pdf-url web-slides-url youtube-url web-url